TGF-β/Smad/ADAMTS-7 Axis Regulates the Process of Curcumin in Promoting the Cartilage Cells Proliferation

To explore the function of curcumin on cartilage cells, cell proliferation and apoptosis by transforming growth factor-beta/suppressor mothers against decapentaplegic/a disintegrin metalloproteinase with thrombospondin motifs-7 axis was objective study. The viability detected counting kit-8. expression factor-beta, suppressor decapentaplegic protein, a motifs-7, caspase-9, B-cell lymphoma 2, Bcl-2-associated X protein determined Western blot. cells were treated 1 mmol/l sodium nitroprusside for 24 h. Then, different concentration We found that μmol/l could recover proliferation. factor-beta show high low in treatment group. Meanwhile, pathway also detected. caspase-9 2 higher group than without However, lower. viability, proteins no changes or when inhibited. over expression, group, curcumin. Curcumin can promote via inhibit apoptosis. indian sex, free porno, kannada desi xxx hd, xnxx video, tamil sex